HID to multiple host devices

Is it possible to map the outputs to more than one device? I’m currently using a two pico variant, and it seems like the following setup would be possible:

Pico A (Pico1) connected to PC-X
Pico A (Pico2) connected to PC-Y
Pico B (Pico3) connected to mouse

Layer 1 output to PC-X and layer 2 output to PC-Y

We did explore this idea with this project based on (an old version of) HID Remapper: